Data sets you free...

Resources and Tools

TCGA Program

A comprehensive and coordinated effort to accelerate our understanding of the molecular basis of cancer through the application of genome analysis technologies, including large-scale genome sequencing.

The program provides detailed genetic and molecular information on various cancers, including hematologic malignancies, and it allows users to analyze genomic data, mutation profiles, and expression patterns across different cancers.

COSMIC

A comprehensive resource on somatic mutations in cancer, covering many hematologic and solid tumors.

Ideal for identifying specific somatic mutations in various cancers, including mutations common in hematologic neoplasms (e.g., JAK2 V617F in MPNs).

Batch Entrez

Batch Entrez is a tool provided by NCBI that allows users to retrieve large sets of biological data, such as genetic sequences or protein information, by submitting a list of accession numbers or identifiers. This batch processing capability streamlines the retrieval of multiple records from NCBI databases.

BLAST

BLAST - Basic Local Alignment Search Tool

BLAST finds regions of similarity between biological sequences. The program compares nucleotide or protein sequences to sequence databases and calculates the statistical significance.

Genome Data Viewer

The Genome Data Viewer (GDV) is a powerful genome browser designed to support the exploration and analysis of annotated genome assemblies. It provides access to both NCBI-annotated and submitter-annotated eukaryotic genome assemblies, including data from over 3,000 organisms. It enables the visualization of a wide range of genomic data, including gene annotations, sequence variations, and experimental data from sources like GEO and dbGaP.

Data

COSMIC

Includes a database of known genes, their genomic context, functional annotations, and related research. It provides insights into gene expression, mutations, and associated diseases, including many related to hematologic malignancies.

Useful for exploring gene mutations and variants linked to hematologic cancers like MPNs, leukemias, and lymphomas.

NCBI Gene Resources

Includes a database of known genes, their genomic context, functional annotations, and related research. It provides insights into gene expression, mutations, and associated diseases, including many related to hematologic malignancies.

Useful for exploring gene mutations and variants linked to hematologic cancers like MPNs, leukemias, and lymphomas.

GTR®

The Genetic Testing Registry (GTR®) provides a central location for voluntary submission of genetic test information by providers. The scope includes the test's purpose, methodology, validity, evidence of the test's usefulness, and laboratory contacts and credentials. The overarching goal of the GTR is to advance the public health and research into the genetic basis of health and disease.

ClinVar

ClinVar aggregates information about genomic variation and its relationship to human health.

dbVar

dbVar is NCBI's database of human genomic Structural Variation — large variants >50 bp including insertions, deletions, duplications, inversions, mobile elements, translocations, and complex variants.

dbSNP

dbSNP contains human single nucleotide variations, microsatellites, and small-scale insertions and deletions along with publication, population frequency, molecular consequence, and genomic and RefSeq mapping information for both common variations and clinical mutations.